Research on alcohol use has examined alcohol-related consequences associated with heavy episodic drinking in undergraduates. This study examined sex differences in alcohol- related consequences. Undergraduates self-reported on positive and negative consequences they experienced during drinking occasions. It was hypothesized that males would experience more positive and negative interpersonal alcohol-related consequences than females, and females would experience more intrapersonal consequences. It was also hypothesized that when alcohol consumption was controlled for, sex differences would be non-significant. The sample consisted of 402 undergraduates with a mean age of 21. Findings indicate that sex is predictive of negative alcohol-related consequences. Both males and females experienced more positive alcohol- related consequences than negative consequences. The results of this study may assist future strategies aimed at interventions related to heavy episodic drinking. Interventions can be based on sex differences in alcohol-related consequences.